Why Circumcision Reduce HIV Risk?
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| BBC |
In a study published in the periodical mbio, the researchers explained that the change in thecommunity of bacteria that live round the penis due to circumcision activities be the reason behind the reduced risk of contracting HIV.
utilising the newest technology so that the sequencing of genes from organisms more quickly and easily accessible, investigators conducted in-depth analysis of the genes of microbes that areround the penis. A total of 156 Ugandan men who were circumcised as adults were respondents in this study. They give samples before circumcision and the year after that.
Although there was no significant distinction in bacterial groups before and after circumcision, but during the period of 12 months later, circumcised men have a number of bacteria that canendure in situation of reduced oxygen (anaerobic) and less bacteria need oxygen (aerobic) more.
In general, the number of circumcised men had a 33 per hundred smaller pathogens that affects the body's proficiency to battle infections such as HIV.
A high number of bacteria, such as the man's penis is not circumcised, will cause Langerhansunits in the skin exterior. These cells are furthermore discovered all over the surface of human skin and commonly actions as the body's first line of defense against pathogens.
In the hardworking status, Langerhans units of HIV transmission verified to be simpler to pull specific units targeted by HIV, the CD4 and T units, and join to it. therefore, healthy unitsbecame very simple targets of HIV.
"There has been a transformation in our understanding of microbes. Microbial actually theidentical as the other organ schemes, and we have arrive to the exterior to realise the connectionbetween microbes and the immune system," said Lance cost, who did this study.
preceding investigations have furthermore shown that changes in bacterial populations in the gut, for demonstration, have an impact on the risk of fatness. Another study also discovered a strong link between the microbial community and the risk factors of cancer, asthma, and other chronic diseases.
(source: the times)
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